Hyaluronidase improves ocular akinesia, patient and surgeon satisfaction, in addition to attenuating postoperative pain.
Amphadase (hyaluronidase injection, USP) is indicated to increase the absorption and dispersion of other injected drugs and contraindicated where hypersensitivities to hyaluronidase or any other ingredient in the formulation exist
| Category | Lidocaine/Hyaluronidase | Lidocane Only |
| Complete Akinesia | 33% | 4.8% |
| Surgeon Satisfaction | 87.5% | 52.4% |
| Patient Satisfaction | 87.7% | 57.1% |
| Pain Control (mean VAS Score) | 1.90 + 1.45 | 3.00 + 1.55 |
Sedghipour M, Mahdavifard A, Fouladi RF, Gharabaghi D, Rahbani M, Amiraslanzadeh G, Afhami M. Hyaluronidase in sub-Tenon’s anesthesia for phacoemulsification, a double-blind randomized clinical trial. Int J Ophthalmol 2012;5(3):389-392